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Polimeni G, Esposito E, Bevelacqua V, Guarneri C, Cuzzocrea S (2014) Role of melatonin supplementation in neurodegenerative disorders

As of June 2026, the FDA's December 2024 Pharmacy Compounding Advisory Committee evaluation concluded that the criteria weighed against placing AOD-9604 (free base) or AOD-9604 acetate on the 503A Bulks List, and AOD-9604 is currently listed as Nominated but Withdrawn from FDA Category 2

This approach is often used in tightly controlled experiments where consistency and simplicity are prioritised

Cureus 15 (12), e50351

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