You are vomiting blood, or the vomit is dark colored (coffee colored)
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When to seek medical advice : Patients should contact their GP or diabetes specialist nurse if they experience: Severe, persistent vomiting preventing adequate fluid intake (risk of dehydration and acute kidney injury) Severe abdominal pain, particularly if radiating to the back (potential pancreatitisrare but serious) Right upper abdominal pain, fever, or yellowing of skin/eyes (potential gallbladder disease) Sudden vision changes (particularly with semaglutide, which may worsen diabetic retinopathy, especially with rapid HbA1c reduction) [40] [41] Signs of hypoglycaemia when used with insulin or sulphonylureas Allergic reactions (rash, difficulty breathing, facial swelling)call 999 or go to A&E for severe allergic reactions Patients should report suspected side effects via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or the Yellow Card app)
Why Individual Timelines Vary: Genetic and Metabolic Factors Your GLP-1 receptor genetics play a decisive role in how quickly semaglutide produces noticeable effects
Reducing cholesterol levels is effective in preventing ASCVD
