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The overweight and obese status in diabetic participants may be implicated to cause an impaired cell response to insulin

Histopatologa Las mculas melanticas labiales se caracterizan por una hiperpigmentacin focal de la hilera basal del epitelio de la mucosa que se acompaa de un nmero normal de melanocitos o slo un discreto aumento de estas clulas a lo largo de la interfase entre epitelio y el corion de la zona de la mucosa afectada

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