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Cancer and the microbiota

d , OCR in gWAT and iWAT mitochondria of Control and Ndufs2 -KO mice at ZT14 in the presence of indicated substrates and inhibitors (n = 7 for gWAT and n = 6 for iWAT)

Mandal PK, Shukla D, Tripathi M, Ersland L (2019) Cognitive improvement with glutathione supplement in Alzheimers disease: a Way Forward

Together, these findings suggest that KYN-driven oxidative stress is not merely an epiphenomenon of depression but a mechanistic contributor to mitochondrial dysfunction, neuroprogression, and systemic comorbidity, highlighting redox modulation as a critical interface between inflammation, KP activity, and depressive pathology

Hepatology 75 , 7488 (2022)