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In addition to reductions in body weight, abdominal fat and liver fat, retatrutide treatment was associated with improvements in insulin sensitivity, lipid metabolism and adipocyte hormones

The Today Show story also cited a research letter published in JAMA (formerly the Journal of the American Medical Association) warning of an increased risk of severe stomach problems for people taking GLP-1 agonists such as Ozempic and Wegovy

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[DOI] [PubMed] [Google Scholar] 129.Wright G, Antonyuk SV, Hasnain SS