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In a study of renal microcirculation in SD rats subjected to intravenous vasoconstriction agents, infusion of NAC improved blood flow and lowered vascular resistance by a mechanism other than NO or prostaglandins (220)

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Decreased cellular adenosine triphosphate production can account for many of the symptoms and signs associated with FMS, including cognitive dysfunction, fatigue, and muscle pain caused by the build-up of anaerobic metabolites such as lactic acid