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It directly activates L-type calcium channels on colonic smooth muscle cells, triggering robust contractions and significantly accelerating the total gut transit time

Compared to injectable peptides, this oral bioavailability offers a practical and non-invasive mode of delivery, which is a major benefit

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But its also one of the hardest to maintain, OKAVA CEO Michael Klotsman says in the statement

Cancer (2007) 110:234762