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A mechanism of CoC bond photolysis in the base-o form of the methylcobalamin cofactor (MeCbl) and the inuence of its axial base on CoC bond photo-dissociation has been investigated by time-dependent density functional theory (TD-DFT)

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2c and Supplementary Table 4)

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Its exact role in each disease differs slightly, but each revolves around GSHs major role as an antioxidant

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DOI: 10.1038/s41586-026-10268-2.

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