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Gastroenterology 136 (4), 14351443

It activates 1,942 genes (including 47 DNA repair genes and 14 antioxidant genes) and suppresses 762 genes involved in inflammation and fibrosis

EGFR antagonists are examples of efforts to modify goblet cell formation and subsequent mucin secretion, but none have progressed

Annihilation of portal hypertension consistently occurred

Although this enhancement in antioxidant defenses was insufficient to fully counteract oxidative stress and apoptosis in HD striatal cells, it partially prevented extensive neuronal death and significant mHtt aggregation, reducing the initial ROS production in mutant cells