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The synthesis of gamma-glutamyl dipeptides was described using a flow chemistry reactor in combination with an immobilized coupling reagent (polymer-supported (PS-HOBt) and scavengers ( The synthesis of H-Glu (Glu-OH)-OH described in Scheme 1 started with suitably commercial protected amino acid without purification

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The early data suggest that Petrelintide could be a highly effective component in combination therapies aimed at maximizing weight loss and improving metabolic health in patients with obesity and type 2 diabetes

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10.1007/s12263-007-0055-0 15 BucioliS