As soon as January 2026, companies like Sandoz and Apotex are expected to launch generic versions of semaglutide in Canada, where protections from data exclusivity will come to an end
We define progressive loss of kidney function as a loss of 1 to 3 mL/min per 1.73 m per year, but consider this abnormal, particularly in people 10-fold the upper limit of normal [26]
Genetic biomarkers for MASLD include DNA sequence variants, such as single nucleotide polymorphism (SNP) and the most studied SNPs in MASLD are rs738409 and rs58542926, which are located in patatin-like phospholipase domain containing protein 3 (PNPLA3) and transmembrane 6 superfamily member 2 (TM6SF2), respectively
Small, frequent meals of 200 to 300 calories work better than large meals during this adjustment window
In contrast, Wegovy is dosed at higher levels specifically optimized for weight loss