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This seemingly minor change -- the addition of a single methyl group -- can influence copper binding geometry, peptide stability, skin penetration, and biological activity

[62] Clarke subsequently administered chelation therapy to patients with angina pectoris and other occlusive vascular disease and published his findings in The American Journal of the Medical Sciences in December 1956

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An innovative ultra thin sheet mask designed to melt seamlessly into the skin when activated with a moisture spray

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