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The other phase IIa study also confirmed improved glycemic control in those with obesity and T2DM, but also reported decreased body weight and improvement of blood lipids compared to placebo [44]
In some cases, semaglutide usage has led to changes in blood sugar levels, which can also affect kidney function
The model finally proposes that the alteration on neurotransmitter transport, microtubule assembling and redox imbalance ends affecting the nervous system of the affected animals, leading to the different abnormal behaviors (ataxic gait and comorbid depression and anxiety disorder) observed in AA-treated zebrafish adults and larvae 7,8,9