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Review Article Abstract Introduction Retatrutide for Treatment of Obesity Retatrutide for Treatment of Type 2 Diabetes Effects of Retatrutide on Cardiovascular Risk Factors Safety of Retatrutide Effect of Retatrutide on Heart Rate Advantages of Retatrutide Limitations of Retatrutide Conclusions and Current Needs References Retatrutide for Treatment of Type 2 Diabetes In another phase 2 trial in the USA, retatrutide was evaluated for treatment of type 2 diabetes in comparison with subcutaneous dulaglutide (1.5mg/weekly) and placebo (Table 1) [4]

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Until recently, only vitamin E and pioglitazone were the only pharmacological agents recommended for off-label use in MASH but more recently, with the U.S