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77,174,175 Of note, GFAP expressed by reactive astrocytes following TBI, or released by damaged or dead astrocytes, can be also detected in the blood and spinal fluid, and the levels of GFAP in these fluids can reflect the severity of trauma and can be used as a diagnostic clinical tool

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166 A recent study reported that S-nitrosylation altered AAT to a proinflammatory protein, which facilitated the inflammatory state of macrophages by upregulating proinflammatory molecules and the activation of MAPK signalling pathways