retatrutide ly3437943 glp-1 gip glucagon is the triple-agonist shaking up metabolic medicine. Activates GLP-1, GIP, and receptors in one shot. Phase 2 results: 24% body weight lost in 48 weeks—nearly double semaglutide. Key edge? Retatrutide Dosage & Titration: Complete

10.1146/annurev.me.40.020189.002211

If we continue covering GLP-1s for weight loss, our forecasts show these drugs will drive an unsustainable increase in the cost of medical coverage for everyonewhether they take the medication or not, read a press release from Blue Cross Blue Shield, which ended coverage January 1

Initially, the agency cited shortages of semaglutide and tirzepatide the active ingredients in the popular drugs Wegovy and Zepbound and allowed pharmacies to compound these drugs under a provision for addressing drug shortages

doi:10.1111/acel.12006

GLP-1 medications influence appetite and glucose regulation, but they do not independently preserve muscle mass