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Furthermore, particulate matter in cigarette smoke activates lung macrophages that subsequently attract neutrophils

That includes investigational products, compounded products, and anything obtained outside standard pharmacy channels

Populo H, Caldas R, Lopes JM, Pardal J, Maximo V, Soares P

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For example, Th1 cells produce IFN- and IL-2, which play a crucial role in activating macrophages and enhancing T cell cytotoxicity (78)