doi: 10.1056/NEJMoa2504214
In a randomized crossover study of young adults, muscle protein synthesis dropped by 18%, while cortisol levels jumped by 21% and testosterone fell by 24%
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The decision was posted on IBXs website in November and drew local press coverage this week
Key Differences Summary# Weight loss : CagriSema achieves ~20.4% vs semaglutide's ~14.9%, a meaningful improvement Mechanism : CagriSema adds amylin pathway to GLP-1