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In animal models, psychosocial stress-induced (neuro) inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression

In this review, we discuss the mechanistic and clinical synergies that make the combined use of GLP-1RAs and SGLT2is appealing in patients with T2DM

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After the final dose, semaglutide can remain in the body for approximately 57 weeks, with conservative clinical guidance often citing up to 8 weeks for near-complete washout