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Both the LEADER (liraglutide) and SUSTAIN-6 (subcutaneous semaglutide) trials reported significant reductions in the primary outcome (incidence of MACE)

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Patients should not seek retatrutide from unregulated online sources, as unlicensed products carry serious risks including contamination and unknown safety profiles

The period 20072018 for registered prescriptions was chosen to ensure a minimum of 3 years of follow-up for all included subjects

B12 and caffeine work through completely different mechanisms B12 supports cellular energy production, while caffeine blocks adenosine receptors to reduce perceived fatigue