Tetrahydrobiopterin (BH4) possesses robust antioxidant properties, enabling it to directly curb lipid peroxidation (69, 70)
Proc Natl Acad Sci USA 2010
Acknowledgments Funding: This work was supported by the National Key Research and Development Program of China (2023YFC2508200), the National Natural Science Foundation of China (82373509, 82003384, and 82203960), Fundamental Research Funds for the Central Universities (2022CDJYGRH-003 and 2023CDJKYJH066), the Natural Science Foundation of Chongqing (CSTB2023JXJL-YFX0028), Chongqing Talents: Exceptional Young Talents Project (cstc2021ycjh-bgzxm0197), Inheritance and Innovation Team of TCM Treatment of Immune Diseases, Scientific Research Foundation from Chongqing University (02210011044110), and Research Horizontal Projects of Chongqing University (H20231432 and H20230936), China
Certain conditions drastically increase risk: PCOS (50% lower glutathione), IVF conception (70-83% depleted antioxidants), gestational blood sugar issues, gallbladder dysfunction (10% of pregnancies), and choline deficiency (89% of pregnant women)
Nutr Metab Insights
