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AAPS J 27 , 45 (2025)

The data for other GLP-1 agonists in the setting of OSA are limited [111], although one study did find that use of exenatide led to subjective improvements in sleepiness in patients with obesity, though this study specifically excluded patients with OSA [112]

By slowing gastric emptying and increasing feelings of satiety, patients often experience reduced appetite and caloric intake, leading to significant weight loss over time

Non-diabetic patients who received 15mg weekly for 72 weeks (about 17 months) lost an average of 22.5% of their body weight, compared to 2.4% of the placebo group

Currently, tens of thousands of people in the United States have restless legs syndrome that is severe enough to disrupt normal daily life