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We used a Mendelian randomization design to test whether this relation might be causal

It is recommended to move the joint minimally

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Checking lyophilized vial integrity after shipping: Open the box, confirm vials are not broken, check for loose caps or visible moisture inside the vial (indicates a seal breach), and confirm the powder is still a dry, uniform cake or fluffy powder

Additionally, more investigation and scientific study is required to determine the correct protocols for best practices, safety, and optimal outcomes