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In a subsequent study using the protein toxin CNF-1 to increase the activity of Rho proteins, it was found that CNF-1 treated mice had an elevated level of actin filaments and enhanced freezing during a fear memory test and better performance in the Morris water maze test (Munro et al., 2004)

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European Journal of Heart Failure, 15 (11), 126776

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Why This Matters These findings likely represent just the tip of the iceberg, reinforcing the need for proactive screening, nutrition support, and multidisciplinary care in patients receiving GLP-1 therapy