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Endothelial dysfunction, which can be detected by the reduction in vascular responsiveness to vasodilators, is a major contributing factor to diabetic cardiovascular complications

In people who are overweight or obese, there is usually a high level of leptin, but that signal isnt being received in the brain (leptin resistance)

Establishing direct cause-and-effect relationships proves challenging due to numerous confounding variables and the complex nature of mental health influences

The dual activation in tirzepatide already showed superior weight loss compared to semaglutide alone