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We found that processing the counts from the 2 cohorts together and correcting for batch effects with ComBat effectively harmonized the data from the 2 cohorts

All authors were involved in the preparation and review of the manuscript and approved the final submitted version

In studies involving the IMQ mouse model, a marked elevation of Tbxar2 mRNA expression has been observed in V4+ T cells, which facilitates the enhanced secretion of IL-17A in these T cells, ultimately contributing to the manifestation of skin lesions reminiscent of psoriasis

Proceedings of the National Academy of Sciences of the United States of America 112, 87688773 (2015)

[10] [11] These findings suggest a potential direct role in bone metabolism