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However, other studies have indicated that POMC GLP-1R knockdown can increase HFD-induced weight gain, and ARC GLP-1R blockade by GLP-1R antagonists attenuated the anorexic effects of liraglutide [57]

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Eating smaller portions of sugar-heavy, low-protein, low-nutrient meals still leaves your body without the building blocks it needs to maintain muscle, regulate appetite, and support metabolic health

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