doi: 10.1021/bi050519d
Its bioactive form, coenzyme A, plays many roles in the body, including the metabolism of proteins, fats and carbohydrates, the production of energy, and the synthesis of red blood cells and the key neurotransmitter, acetylcholine
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TH acts to increase LDL-R expression in part through direct recruitment of the THR to the LDL-R promoter and, second, through the activation of sterol regulatory element-binding protein 2 ( SREBP2 ), which increases LDL-R transcription (Figure 3A)
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