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Estradiol has been related to the modulation of appetite and the balance of glycemia, having a crucial role in the maintenance of the metabolic homeostasis and body weight (Rubinow, 2017)

It can be surmised that the higher GST activity helps to re-establish the balance between pro-oxidative damage and antioxidants to ease ROS induced oxidative damage

Marino et al., 2012

[9] Therapy-resistant cancer cells in a high-mesenchymal state depend on a lipid peroxidase pathway to suppress ferroptosis, indicating a critical survival mechanism in this cellular context

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