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Zinc In a meta-analysis of 4 randomized controlled trials of oral zinc supplementation (zinc acetate, sulfate, or carnosate) in 223 patients with hepatic encephalopathy resulting from cirrhosis, three trials showed improvements in cognitive function compared to baseline measurements (Chavez-Tapia 2013)

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For most people, the practical approach involves working with a healthcare provider to establish a baseline through blood work, then adjusting session frequency based on symptom improvement and lab results

It also normalized levels of neurotransmitters and hormones in various stress conditions (leading some to propose it has a balancing effect on the brain-gut axis )

doi: 10.1016/j.cell.2014.11.048