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This adverse effect likely stems from interference with dopamine synthesis, as DFP reduces iron availability for tyrosine hydroxylase, a key enzyme

Additional genes, including NDUFA4 mitochondrial complex associated like 2 ( NDUFA4L2 ), which downregulates mitochondrial OXPHOS activity to reduce oxidative stress, optimizing survival in low-oxygen environments [54], were also upregulated (Fig 3B)

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