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Vitamin B3: Niacin (vitamin B3) is a strong vasodilator, meaning it dilates blood vessels to allow more oxygen and nutrients to enter the body, especially the brain

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It is not clear whether other factors affect adverse pregnancy outcomes in patients with AITD ( Statements Author contributions YS: Writing original draft, Writing review & editing

The long-term effects on growth hormone secretion are of specific interest, as sustained rise of IGF-1 levels (whether from endogenous or exogenous sources) can suppress growth hormone release through negative feedback at the hypothalamic and pituitary levels