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Plasmid-based gene therapy with hepatocyte growth factor stimulates peripheral nerve regeneration after traumatic injury

We established that Fbx2 overexpression in primary neurons derived from Tg2576 transgenic mice, a well characterized AD mouse model (Hsiao et al., in vivo studies with Tg2576 mice, we found that stereotactic delivery of adenoviral-Fbx2 to the brain significantly increased Fbx2 expression and decreased synaptic deficits coinciding with a reduction of BACE1, which is essential for A formation (Gong et al., 2005

Cortisone injections have become less in vogue medically due to their harmful side effects, including loss of muscle tissue, damage to ligaments and tendons, and bone loss

Antioxidants (Basel) 7 (5), 63