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This modification enhances NNTs affinity for its substrate NADP+, promoting NADPH synthesis, maintaining ironsulfur cluster homeostasis, lowering intracellular ferrous iron levels and lipid peroxidation, and thereby protecting tumor cells from ferroptosis (118)
10.1111/j.1469-0691.2005.01227.x Clin
Its decreasing levels can contribute to such chronic diseases as cardiovascular issues, diabetes, and cancer The production of glutathione can decline with age or in response to excessive stress and toxin exposure
revealed that keeping EVs in PBS throughout time reduces recovery rates, especially for pure samples
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