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Thus, to maximize therapeutic outcomes, novel designs are required to advance the facile integration of different therapeutics onto platelet carriers, progressively improve both binding and penetration in atherosclerotic lesions, and ensure on-demand drug delivery to plaque macrophages

Rights and permissions About this article Cite this article Arvin, A.M., Fink, K., Schmid, M.A

In general, dose increases are typically spaced at least 4 weeks apart to help assess tolerability