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A phase 3b, interventional, adaptive, clinical trial to evaluate the efficacy and safety of tralokinumab 300 mg every second week monotherapy compared with placebo in subjects with moderate-to-severe atopic hand eczema who are candidates for systemic therapy

The primary pharmacology involves inhibition of the inactivation of GLP-1 and GIP, which leads to the important effects to stimulate insulin secretion and inhibit glucagon secretion in a glucose-dependent manner (145)

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Hypertension 53 , 668673 (2009)