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Anti-depressants, which increase BDNF levels, lead to improvements in depressive behavior in BDNF-deletion mutant mice (Taliaz et al., 2010

However, these positive benefits in animal studies have apparently not been translated into likely beneficial clinical outcomes

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However, these drug-linked interruptions in food noise wore off after a few months, suggesting that tirzepatide is not a permanent solution to conditions such as binge eating