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, 2015), preventing browning (Comuzzo and Zironi, 2013

Yu Cao is the editorial board member of Signal Transduction and Targeted Therapy, but she has not been involved in the process of manuscript handling

In addition, dysregulated mitochondrial biogenesis and excessive ATP release under oxidative conditions act as damage-associated molecular patterns (DAMPs), activating inflammasomes and enhancing chemotactic signals for immune cells like CD8 + T cells 67

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During this process, pre-luminal ( SULT1E1 ) and pre-glandular ( OPRK1 , SUFU , CBR3 , HPRT1 ) cells differentiate into mature luminal ( WNT7A , LGR5 , PTGS1 ) and glandular ( ITGA1 , HPGD , SLC47A1 ) cells, respectively [25]