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Step 2: Reduced Oxidative Stress in Skin Tissue Skin is your most exposed organ
I couldn't really tell you what the mechanism, I don't remember
As mentioned above, oxidative stress contributes to hypothyroidism
In addition, as shown using an animal model of congestive heart failure (CHF), GH prevented the atrophy and the shift from slow-twitch fibers to fast-twitch and more fatigable glycolytic fibers which works as an adaptation mechanism of the skeletal muscle to a low cardiac output characterizing the muscle atrophy as a common sign of patients with advanced CHF (206)
Therefore, these populations should avoid using them
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