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Expert Opinion on Biological Therapy, 18(sup1), 131139

Conclusions HT is an autoimmune disease with multifactorial and still not entirely known etiology

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As a consequence, we propose that the excreted amount of sulforaphane metabolites (sulforaphane + sulforaphane cysteine-glycine + sulforaphane cysteine + sulforaphane N-acetylcysteine) in urine over 24 h (23 half-lives), which is a measure of internal dose, provides a more revealing and likely consistent view of the delivery of sulforaphane to study participants

Surgery: When conservative treatments have not been effective, or if the injury is severe, surgery may be necessary