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10.22038/IJBMS.2017.8847 134 SalehpourF.Sadigh-EteghadS.MahmoudiJ.KamariF.CassanoP.HamblinM

Maintaining proper calcium balance is essential for numerous physiological processes in the human body

A lack of riboflavin can show up as: angular cheilitis (cracks at the corners of the mouth) anemia burning mouth sore throat cataracts Riboflavin deficiency can also cause problems with iron absorption, leading to iron-deficiency anemia

LDDD is caused by the natural aging process, where the intervertebral discs lose hydration and become less elastic, leading to degeneration

FIGURE 5 5.3.1 ROS-mediated inhibition of the AMPK pathway and antioxidant defense AMP-activated protein kinase (AMPK) is a central regulator of cellular energy sensing and redox homeostasis in skeletal muscle (Ren et al., 2021)