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Bring your symptom diary if you have kept one, and be ready to describe: When symptoms began in relation to starting or increasing the dose How often you are experiencing bowel changes and what they look like Whether symptoms are improving, worsening, or staying the same What you have already tried to manage them and whether it helped How much the symptoms are affecting your daily life and wellbeing Your prescriber may consider adjusting your dose-escalation schedule, recommending specific dietary changes, or referring you to a gastroenterologist if symptoms are complex or persistent

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BARI-OPTIMISE demonstrated comparatively higher %WL to the SCALE trial

However, its use is not advised for treating type 1 diabetes