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Understanding this window gives you confidence that a minor timing slip won't undo weeks of progress

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6, 32 Thus, early diagnosis provided by identification through universal NBS for HT-1 and immediate initiation of therapy should provide the most favorable outcomes for patients

Reports of adverse events and contamination exist, raising concerns about their use

If GSH is severely depleted by the toxic metabolite of acetaminophen, NAPQI (Figure 3b), and/or there is inadequate glycine to produce GSH due to illness or nutritional deficiency, there is a lack of negative feedback of GSH on -glutamylsynthetase