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Figure 5 In addition, ATP serves as a neurotransmitter, co-transmitter, and neuromodulator, undertaking an important role in pain processing, and ATP P1 receptors (A1, A2A, A2B, and A3) are found ubiquitously expressed in the nervous system (Franco et al., 2021)

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39 Study of this potential interaction is particularly important due, in part, to the effect of omeprazole on stomach pH and the complicated interplay between SNAC and gastric pH to allow for oral semaglutide absorption