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Given the effects on immune health, NSW and sleep disruption can affect vaccine efficacy

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Abbreviations: AM (alveolar macrophage), BAL (bronchoalveolar lavage), DC (dendritic cell), e-cig (e-cigarette), e-cig vaped extract (EVE), gen (generation), h (hour), min (minute), NK (natural killer), PG (propylene glycol), THC (tetrahydrocannabinol), VG (vegetable glycerin) Summary of E-cigarette Effects in the Circulation: E-cigarettes increase systemic inflammation, as indicated by elevated pro-inflammatory cytokines and lipid mediators, and some of these effects are rapidly reversible in the setting of reduced e-cigarette use (Table 14)

But people who follow a vegetarian or vegan diet should eat nutritional yeast and other foods fortified with vitamin B-12

Mol Nutr Food Res 61(1):1600240 Gu Z, Liu Y, Hu S, You Y, Jiaqi W, Li W, Wang Y (2019) Probiotics for alleviating alcoholic liver injury