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The discovery, preclinical, and early clinical development of potent and selective GPR40 agonists for the treatment of type 2 diabetes mellitus (LY2881835, LY2922083, and LY2922470)

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This may be why there arent currently any studies that have explored this method of delivery

Multi-ligand strategies and optimized surface chemistry further enhance transport efficiency, offering a pathway toward clinically relevant brain-targeted delivery systems