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doi: 10.3389/fnagi.2026.1689139 Received 20 August 2025 Revised 19 December 2025 Accepted 15 January 2026 Published 04 February 2026 Volume 18 - 2026 Edited by Pei Shang, Mayo Clinic, United States Reviewed by Maria Bayliak, Vasyl Stefanyk Precarpathian National University, Ukraine Johannes Riegler, Calico Life Sciences LLC, United States Updates Copyright 2026 Jamerson, Bradshaw and Bradshaw

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Gather Supplies Essential items : Before you begin, ensure you have the following: Your GLP-1 medication pen (or vial and insulin injection needles in the case of compounded medication) Alcohol swabs for skin disinfection

This simplification makes the math clean and accurate

Group 6 consists of 4 mice, as prior experiments showed acceptable variability