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A non-randomized clinical trial conducted on hemodialysis patients revealed that 15 mg/kg LC 3 times per week (after each hemodialysis session) for 6 months can increase Alb, total protein, glutathione (GSH), GSH peroxidase, and decrease MDA, but cannot change SOD and serum antioxidant capacity significantly [35]

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doi:10.1007/s40279-015-0398-4

Food and Drug Administration (FDA) removed the prescribing restrictions associated with rosiglitazone following the release of the RECORD study, which showed that patients taking rosiglitazone were not at higher risk of heart attack or death compared with patients treated with other medications (hazard ratio [HR] = 0.99