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Huang YS, Chang CH, Lin TL, Perng CL (2014) Genetic variations of superoxide dismutase 2 and cytochrome P450 2E1 in non-alcoholic steatohepatitis

Depletion of antioxidant systems in neurons, especially the glutathione system, leads to an increase in neuroinflammation and has an important role in the pathogenesis of neurodegenerative disorders [94,95,96]

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In contrast to PIO, rosiglitazone was not shown to promote histologic improvements of NASH during a 12-month well-organized study [65]