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THE NNMT INHIBITOR MECHANISM 5-Amino-1MQ (also referred to as 5-amino-1-methylquinolinium) is a small-molecule organic compound that functions as a potent, selective inhibitor of NNMT (nicotinamide N-methyltransferase)

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Research Overview Nicotinamide N-methyltransferase (NNMT) catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide, producing 1-methylnicotinamide and S-adenosyl-L-homocysteine [1]